Dataset Information

Bundled care for septic shock: an analysis of clinical trials.

ABSTRACT:

Context

Sepsis bundles have been developed to improve patient outcomes by combining component therapies. Valid bundles require effective components with additive benefits. Proponents encourage evaluation of bundles, both as a whole and based on the performance of each component.

Objective

Assess the association between outcome and the utilization of component therapies in studies of sepsis bundles.

Data source

Database searches (January 1980 to July 2008) of PubMed, Embase, and the Cochrane Library, using the terms sepsis, bundles, guidelines, and early goal directed therapy.

Data extraction

Inclusion required comparison of septic adults who received bundled care vs. nonprotocolized care. Survival and use rates for individual interventions were abstracted.