Comparison of arterial spin labeling and bolus perfusion-weighted imaging for detecting mismatch in acute stroke.

ABSTRACT:

Background and purpose

The perfusion-weighted imaging (PWI)-diffusion-weighted imaging (DWI) mismatch paradigm is widely used in stroke imaging studies. Arterial spin labeling (ASL) is an alternative perfusion method that does not require contrast. This study compares the agreement of ASL-DWI and PWI-DWI mismatch classification in patients with stroke.

Methods

This was a retrospective study drawn from all 1.5-T MRI studies performed in 2010 at a single institution. Inclusion criteria were: symptom onset<5 days, DWI lesion>10 mL, and acquisition of both PWI and ASL. DWI and PWI time to maximum>6 seconds lesion volumes were determined using automated software. Patients were classified into reperfused, matched, or mismatch groups. Two radiologists classified ASL-DWI qualitative

SUBMITTER: Zaharchuk G 

PROVIDER: S-EPMC3383868 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature