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Variation in genomic islands contribute to genome plasticity in Cupriavidus metallidurans.


ABSTRACT:

Background

Different Cupriavidus metallidurans strains isolated from metal-contaminated and other anthropogenic environments were genotypically and phenotypically compared with C. metallidurans type strain CH34. The latter is well-studied for its resistance to a wide range of metals, which is carried for a substantial part by its two megaplasmids pMOL28 and pMOL30.

Results

Comparative genomic hybridization (CGH) indicated that the extensive arsenal of determinants involved in metal resistance was well conserved among the different C. metallidurans strains. Contrary, the mobile genetic elements identified in type strain CH34 were not present in all strains but clearly showed a pattern, although, not directly related to a particular biotope nor location (geographical). One gro

SUBMITTER: Van Houdt R 

PROVIDER: S-EPMC3384475 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature