Pt(II)-catalyzed synthesis of 1,2-dihydropyridines from aziridinyl propargylic esters.

ABSTRACT: Pt(II)-catalyzed cycloisomerization of aziridinyl propargylic esters affords 1,2-dihydropyridines with regiodefined installation of substituents. A mild conversion of the 1,2-dihydropyridines to the corresponding substituted pyridines as well as chirality retention from the aziridinyl propargylic ester substrates have been demonstrated.

SUBMITTER: Motamed M 

PROVIDER: S-EPMC3384524 | biostudies-literature | 2007 May

REPOSITORIES: biostudies-literature