Pt-catalyzed cyclization/1,2-migration for the synthesis of indolizines, pyrrolones, and indolizinones.

ABSTRACT: Indolizine, pyrrolone, and indolizinone heterocycles are easily accessed via the Pt(II)-catalyzed cycloisomerization or a tandem cyclization/1,2-migration of pyridine propargylic alcohols and derivatives. This method provides an efficient synthesis of highly functionalized heterocycles from readily available substrates. [reaction: see text]

SUBMITTER: Smith CR 

PROVIDER: S-EPMC3384527 | biostudies-literature | 2007 Mar

REPOSITORIES: biostudies-literature