Molecular Monitoring of Plasmodium vivax Infection after Radical Treatment in Southeastern Iran.

ABSTRACT:

Background

The aim was to evaluate the relapse risk of vivax malaria in patients who received radical treatment in Hormozgan Province, a malarious area located on southeast of Iran.

Methods

A total of 95 symptomatic vivax malaria infected patients were enrolled in urban health centers of Bandar-Abbas, Minab, Bandar-Jask and Bashagard districts of Hormozgan Province, southeast of Iran from January 2008 to March 2009 for consideration as a case- series study. DNA was extracted from parasite infected whole blood samples. A polymorphic region of Plasmodium vivax merozoite surface protein 1 (pvMSP1) was selected and a PCR method was employed for all the samples to amplify the specific variable gene fragment. The obtained fragments in primary and secondary samples were sequenced.

SUBMITTER: Nateghpour M 

PROVIDER: S-EPMC3385539 | biostudies-literature | 2010

REPOSITORIES: biostudies-literature