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Imaging the sialome during zebrafish development with copper-free click chemistry.

ABSTRACT: The sialome comprises sialylated glycoproteins and glycolipids that play essential roles in cell-cell communication. Using azide-modified molecular precursors of sialic acids and copper-free click chemistry, we visualized the spatiotemporal dynamics of the sialome in live zebrafish embryos.

SUBMITTER: Dehnert KW

PROVIDER: S-EPMC3385855 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature

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Imaging the sialome during zebrafish development with copper-free click chemistry.

Dehnert Karen W KW Baskin Jeremy M JM Laughlin Scott T ST Beahm Brendan J BJ Naidu Natasha N NN Amacher Sharon L SL Bertozzi Carolyn R CR

Chembiochem : a European journal of chemical biology 20120120 3

The sialome comprises sialylated glycoproteins and glycolipids that play essential roles in cell-cell communication. Using azide-modified molecular precursors of sialic acids and copper-free click chemistry, we visualized the spatiotemporal dynamics of the sialome in live zebrafish embryos. ...[more]

PMID: 22262667

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