Ontology highlight
ABSTRACT:
SUBMITTER: Ahfeldt T
PROVIDER: S-EPMC3385947 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Nature cell biology 20120115 2
The utility of human pluripotent stem cells is dependent on efficient differentiation protocols that convert these cells into relevant adult cell types. Here we report the robust and efficient differentiation of human pluripotent stem cells into white or brown adipocytes. We found that inducible expression of PPARG2 alone or combined with CEBPB and/or PRDM16 in mesenchymal progenitor cells derived from pluripotent stem cells programmed their development towards a white or brown adipocyte cell fa ...[more]