FT-IR spectroscopic imaging of reactions in multiphase flow in microfluidic channels.

ABSTRACT: Rapid, in situ, and label-free chemical analysis in microfluidic devices is highly desirable. FT-IR spectroscopic imaging has previously been shown to be a powerful tool to visualize the distribution of different chemicals in flows in a microfluidic device at near video rate imaging speed without tracers or dyes. This paper demonstrates the possibility of using this imaging technology to capture the chemical information of all reactants and products at different points in time and space in a two-phase system. Differences in the rates of chemical reactions in laminar flow and segmented flow systems are also compared. Neutralization of benzoic acid in decanol with disodium phosphate in water has been used as the model reaction. Quantitative information, such as concentration profiles of reac

SUBMITTER: Chan KL 

PROVIDER: S-EPMC3386657 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature