Coronary collaterals and risk for restenosis after percutaneous coronary interventions: a meta-analysis.

ABSTRACT:

Background

The benefit of the coronary collateral circulation (natural bypass network) on survival is well established. However, data derived from smaller studies indicates that coronary collaterals may increase the risk for restenosis after percutaneous coronary interventions. The purpose of this systematic review and meta-analysis of observational studies was to explore the impact of the collateral circulation on the risk for restenosis.

Methods

We searched the MEDLINE, EMBASE and ISI Web of Science databases (2001 to 15 July 2011). Random effects models were used to calculate summary risk ratios (RR) for restenosis. The primary endpoint was angiographic restenosis > 50%.

Results

A total of 7 studies enrolling 1,425 subjects were integrated in this analysis. On aver

SUBMITTER: Meier P 

PROVIDER: S-EPMC3386894 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature