The impact of age and gender on papillary thyroid cancer survival.

ABSTRACT:

Context

Thyroid cancer predominately affects women, carries a worse prognosis in older age, and may have higher mortality in men. Superimposed on these observations is the fact that most women have attained menopause by age 55 yr.

Objective

The objective of the study was to determine whether men contribute disproportionately to papillary thyroid cancer (PTC) mortality or whether menopause affects PTC prognosis.

Design

Gender-specific mortality was normalized using age-matched subjects from the U.S. population. Multivariate Cox proportional hazard regression models incorporating gender, age, and National Thyroid Cancer Treatment Cooperative Study Group stage were used to model disease-specific survival (DSS).

Participants and setting

Patients were followed in a

SUBMITTER: Jonklaas J 

PROVIDER: S-EPMC3387425 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature