Infant sleep after immunization: randomized controlled trial of prophylactic acetaminophen.

ABSTRACT:

Objective

To determine the effects of acetaminophen and axillary temperature responses on infant sleep duration after immunization.

Methods

We conducted a prospective, randomized controlled trial to compare the sleep of 70 infants monitored by using ankle actigraphy for 24 hours before and after their first immunization series at ∼2 months of age. Mothers of infants in the control group received standard care instructions from their infants' health care provider, and mothers of infants in the intervention group were provided with predosed acetaminophen and instructed to administer a dose 30 minutes before the scheduled immunization and every 4 hours thereafter, for a total of 5 doses. Infant age and birth weight and immunization factors, such as acetaminophen use and timing

SUBMITTER: Franck L 

PROVIDER: S-EPMC3387894 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature