Flavobacterium johnsoniae RemA is a mobile cell surface lectin involved in gliding.

ABSTRACT: Cells of Flavobacterium johnsoniae move rapidly over surfaces by a process known as gliding motility. Gld proteins are thought to comprise the motor that propels the cell surface adhesin SprB. Cells with mutations in sprB are partially defective in motility and are also resistant to some bacteriophages. Transposon mutagenesis of a strain carrying a deletion spanning sprB identified eight mutants that were resistant to additional phages and exhibited reduced motility. Four of the mutants had transposon insertions in remA, which encodes a cell surface protein that has a lectin domain and appears to interact with polysaccharides. Three other genes identified in this screen (remC, wza, and wzc) encode proteins predicted to be involved in polysaccharide synthesis and secretion. Myc-tagged versi

SUBMITTER: Shrivastava A 

PROVIDER: S-EPMC3393505 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature