PRince: a web server for structural and physicochemical analysis of protein-RNA interface.

ABSTRACT: We have developed a web server, PRince, which analyzes the structural features and physicochemical properties of the protein-RNA interface. Users need to submit a PDB file containing the atomic coordinates of both the protein and the RNA molecules in complex form (in '.pdb' format). They should also mention the chain identifiers of interacting protein and RNA molecules. The size of the protein-RNA interface is estimated by measuring the solvent accessible surface area buried in contact. For a given protein-RNA complex, PRince calculates structural, physicochemical and hydration properties of the interacting surfaces. All these parameters generated by the server are presented in a tabular format. The interacting surfaces can also be visualized with software plug-in like Jmol. In addition, t

SUBMITTER: Barik A 

PROVIDER: S-EPMC3394290 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature