Antimicrobial effect of diallyl sulphide on Campylobacter jejuni biofilms.

ABSTRACT:

Objectives

Bacterial biofilms pose significant food safety risks because of their attachment to fomites and food surfaces, including fresh produce surfaces. The purpose of this study was to systematically investigate the activity of selected antimicrobials on Campylobacter jejuni biofilms.

Methods

C. jejuni biofilms and planktonic cells were treated with ciprofloxacin, erythromycin and diallyl sulphide and examined using infrared and Raman spectroscopies coupled with imaging analysis.

Results

Diallyl sulphide eliminated planktonic cells and sessile cells in biofilms at a concentration that was at least 100-fold less than used for either ciprofloxacin or erythromycin on the basis of molarity. Distinct cell lysis was observed in diallyl sulphide-treated planktonic cells

SUBMITTER: Lu X 

PROVIDER: S-EPMC3394439 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature