Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos).

ABSTRACT:

Background

Radiofrequency ablation (RFA) is an endoscopic technique used to eradicate Barrett's esophagus (BE). However, such ablation can commonly lead to neosquamous epithelium overlying residual BE glands not visible by conventional endoscopy and may evade detection on random biopsy samples.

Objective

To demonstrate the capability of endoscopic 3-dimensional optical coherence tomography (3D-OCT) for the identification and characterization of buried glands before and after RFA therapy.

Design

Cross-sectional study.

Setting

Single teaching hospital.

Patients

Twenty-six male and 1 female white patients with BE undergoing RFA treatment.

Interventions

3D-OCT was performed at the gastroesophageal junction in 18 patients before attaining complete erad

SUBMITTER: Zhou C 

PROVIDER: S-EPMC3396122 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature