Neural circuitry underlying Drosophila female postmating behavioral responses.

ABSTRACT:

Background

After mating, Drosophila females undergo a remarkable phenotypic switch resulting in decreased sexual receptivity and increased egg laying. Transfer of male sex peptide (SP) during copulation mediates these postmating responses via sensory neurons that coexpress the sex-determination gene fruitless (fru) and the proprioceptive neuronal marker pickpocket (ppk) in the female reproductive system. Little is known about the neuronal pathways involved in relaying SP-sensory information to central circuits and how these inputs are processed to direct female-specific changes that occur in response to mating.

Results

We demonstrate an essential role played by neurons expressing the sex-determination gene doublesex (dsx) in regulating the female postmating response. We unco

SUBMITTER: Rezaval C 

PROVIDER: S-EPMC3396843 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature