Cardiovascular safety of central nervous system stimulants in children and adolescents: population based cohort study.

ABSTRACT:

Objectives

To evaluate the cardiac safety of central nervous system stimulants in children and adolescents.

Design

Population based retrospective cohort study.

Setting

Automated healthcare claims data from 1,219,847 children and young people eligible for 28 state Medicaid programmes from 1999 to 2006 linked to the Social Security Death Master File and the National Death Index.

Participants

Children and young people age 3-18 entered the cohort at the first diagnosis of a mental health condition commonly treated with stimulants (such as attention-deficit/hyperactivity disorder) after a minimum period of six months' eligibility and were followed until loss of eligibility, their 19th birthday, admission to hospital for longer than 30 days, or death. Exclusion crite

SUBMITTER: Winterstein AG 

PROVIDER: S-EPMC3399772 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature