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MiRcode: a map of putative microRNA target sites in the long non-coding transcriptome.

ABSTRACT:

Summary

Although small non-coding RNAs, such as microRNAs, have well-established functions in the cell, long non-coding RNAs (lncRNAs) have only recently started to emerge as abundant regulators of cell physiology, and their functions may be diverse. A small number of studies describe interactions between small and lncRNAs, with lncRNAs acting either as inhibitory decoys or as regulatory targets of microRNAs, but such interactions are still poorly explored. To facilitate the study of microRNA-lncRNA interactions, we implemented miRcode: a comprehensive searchable map of putative microRNA target sites across the complete GENCODE annotated transcriptome, including 10 419 lncRNA genes in the current version.

Availability

http://www.mircode.org

Contact

erik.larsson@gu.se

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Jeggari A

PROVIDER: S-EPMC3400968 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature

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miRcode: a map of putative microRNA target sites in the long non-coding transcriptome.

Jeggari Ashwini A Marks Debora S DS Larsson Erik E

Bioinformatics (Oxford, England) 20120619 15

<h4>Summary</h4>Although small non-coding RNAs, such as microRNAs, have well-established functions in the cell, long non-coding RNAs (lncRNAs) have only recently started to emerge as abundant regulators of cell physiology, and their functions may be diverse. A small number of studies describe interactions between small and lncRNAs, with lncRNAs acting either as inhibitory decoys or as regulatory targets of microRNAs, but such interactions are still poorly explored. To facilitate the study of mic ...[more]

PMID: 22718787

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