Ontology highlight
ABSTRACT:
SUBMITTER: Najm FJ
PROVIDER: S-EPMC3400969 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Nature methods 20110925 11
Myelin-related disorders such as multiple sclerosis and leukodystrophies, for which restoration of oligodendrocyte function would be an effective treatment, are poised to benefit greatly from stem cell biology. Progress in myelin repair has been constrained by difficulties in generating pure populations of oligodendrocyte progenitor cells (OPCs) in sufficient quantities. Pluripotent stem cells theoretically provide an unlimited source of OPCs, but current differentiation strategies are poorly re ...[more]