Bottom-up engineering of biological systems through standard bricks: a modularity study on basic parts and devices.

ABSTRACT:

Background

Modularity is a crucial issue in the engineering world, as it enables engineers to achieve predictable outcomes when different components are interconnected. Synthetic Biology aims to apply key concepts of engineering to design and construct new biological systems that exhibit a predictable behaviour. Even if physical and measurement standards have been recently proposed to facilitate the assembly and characterization of biological components, real modularity is still a major research issue. The success of the bottom-up approach strictly depends on the clear definition of the limits in which biological functions can be predictable.

Results

The modularity of transcription-based biological components has been investigated in several conditions. First, the activity o

SUBMITTER: Pasotti L 

PROVIDER: S-EPMC3401228 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature