β-Blocker treatment during pregnancy and adverse pregnancy outcomes: a nationwide population-based cohort study.

ABSTRACT: To investigate the association between exposure to β-blockers during pregnancy and the risk of being born small for gestational age (SGA), preterm birth and perinatal mortality in a nationwide cohort. A population-based retrospective cohort study, using the Danish Fertility Database. The authors identified all pregnant women redeeming a prescription for β-blockers using the National Prescription Registry. Multivariate logistic regression models were used to assess the association between exposure and our outcomes. Register-based survey. 911'685 births between 1995 and 2008 obtained from the Danish Fertility Database. Being born SGA was defined as having a birth weight below the 10th percentile for the corresponding gestational week. Preterm birth was defined as birth before the 37th gestat

SUBMITTER: Meidahl Petersen K 

PROVIDER: S-EPMC3401834 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature