Responses to high-fat challenges varying in fat type in subjects with different metabolic risk phenotypes: a randomized trial.

ABSTRACT:

Background

The ability of subjects to respond to nutritional challenges can reflect the flexibility of their biological system. Nutritional challenge tests could be used as an indicator of health status but more knowledge on metabolic and immune responses of different subjects to nutritional challenges is needed. The aim of this study was to compare the responses to high-fat challenges varying in fat type in subjects with different metabolic risk phenotypes.

Methodology/principal findings

In a cross-over design 42 men (age 50-70 y) consumed three high-fat shakes containing saturated fat (SFA), monounsaturated fat (MUFA) or n-3 polyunsaturated (PUFA). Men were selected on BMI and health status (lean, obese or obese diabetic) and phenotyped with MRI for adipose tissue distribu

SUBMITTER: van Dijk SJ 

PROVIDER: S-EPMC3402390 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature