Stability of synchronization clusters and seizurability in temporal lobe epilepsy.

ABSTRACT:

Purpose

Identification of critical areas in presurgical evaluations of patients with temporal lobe epilepsy is the most important step prior to resection. According to the "epileptic focus model", localization of seizure onset zones is the main task to be accomplished. Nevertheless, a significant minority of epileptic patients continue to experience seizures after surgery (even when the focus is correctly located), an observation that is difficult to explain under this approach. However, if attention is shifted from a specific cortical location toward the network properties themselves, then the epileptic network model does allow us to explain unsuccessful surgical outcomes.

Methods

The intraoperative electrocorticography records of 20 patients with temporal lobe epilepsy wer

SUBMITTER: Palmigiano A 

PROVIDER: S-EPMC3402406 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature