Associations between apolipoprotein E genotype, diet, body mass index, and serum lipids in Lithuanian adult population.

ABSTRACT:

Background

Apolipoprotein E (APOE) polymorphism is associated with lipid levels. Some studies have reported that blood lipid response to diet or obesity varies depending on APOE genotypes. The aim of this study was to assess the effect of APOE genotypes, the intake of saturated fatty acids (SFA), and obesity on serum lipid levels in Lithuanian adult population.

Methodology/principal findings

A cross-sectional health survey was carried out in five municipalities of Lithuania. The random sample was obtained from lists of 25-64 year-old inhabitants registered at primary health care centres. The data from 996 subjects (416 men and 580 women) were analysed in this study. Two single-nucleotide polymorphisms (rs429358 and rs7412) were assessed using a real-time polymerase chain rea

SUBMITTER: Petkeviciene J 

PROVIDER: S-EPMC3402524 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature