Is MRI better than CT for detecting a vascular component to dementia? A systematic review and meta-analysis.

ABSTRACT:

Background

Identification of causes of dementia soon after symptom onset is important, because appropriate treatment of some causes of dementia can slow or halt its progression or enable symptomatic treatment where appropriate. The accuracy of MRI and CT, and whether MRI is superior to CT, in detecting a vascular component to dementia in autopsy confirmed and clinical cohorts of patients with VaD, combined AD and VaD ("mixed dementia"), and AD remain unclear. We conducted a systematic review and meta-analysis to investigate this question.

Methods

We searched eight databases and screened reference lists to identify studies addressing the review question. We assessed study quality using QUADAS. We estimated summary diagnostic accuracy according to imaging finding, and ratios o

SUBMITTER: Beynon R 

PROVIDER: S-EPMC3403932 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature