Malignancy validation in a United States registry of rheumatoid arthritis patients.

ABSTRACT:

Background

Physician reporting is commonly used to ascertain adverse events or outcomes measured in epidemiologic studies. However, little is known on the accuracy of physician reported malignancies compared to pertinent medical record review in large cohort studies.

Methods

The Consortium of Rheumatology Researchers of North America (CORRONA) registry gathers physician-completed questionnaires for rheumatoid arthritis (RA) patients, including request for information on incident malignancies, approximately every three months. For incident malignancies reported from October 1st, 2001, through December 31st, 2007, we retrospectively requested completion of a Targeted Adverse Event (TAE) form for additional information as well as primary source documents to adjudicate the malig

SUBMITTER: Fisher MC 

PROVIDER: S-EPMC3403943 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature