Rubella epidemics and genotypic distribution of the rubella virus in Shandong Province, China, in 1999-2010.

ABSTRACT:

Background

The rubella vaccine was introduced into the immunization program in 1995 in the Shandong province, China. A series of different rubella vaccination strategies were implemented at different stages of measles control in Shandong province.

Methodology/principal findings

The average reported incidence rate of rubella cases remained at a low level in Shandong province after 1999. However, rubella epidemics occurred repeatedly in 2001/2002, 2006, and 2008/2009. The age of the onset of rubella cases gradually increased during 1999-2010, which showed that most cases were found among the 10 years old in 1999 and among the 17 years old in 2010. Phylogenetic analysis was performed and a phylogenetic tree was constructed based on the World Health Organization standard sequenc

SUBMITTER: Wang C 

PROVIDER: S-EPMC3404038 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature