Risk of cancer with metal-on-metal hip replacements: population based study.

ABSTRACT:

Objective

To assess the risk of cancer associated with modern primary metal-on-metal hip replacements.

Design

Population based study.

Setting

Nationwide retrospective comparative register.

Participants

10,728 patients who underwent metal-on-metal total hip arthroplasty and 18,235 patients who underwent conventional metal-on-polyethylene, ceramic-on-polyethylene, and ceramic-on-ceramic total hip arthroplasty (the non-metal-on-metal cohort) in the Finnish Arthroplasty Register 2001-10. Data on cancer cases up to 2010 for these cohorts were extracted from the Finnish Cancer Registry.

Main outcome measures

The relative risk of cancer was expressed as the ratio of observed to expected number of cases from the Finnish population--that is, the standardised inci

SUBMITTER: Makela KT 

PROVIDER: S-EPMC3404595 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature