Genome-wide characterization of genetic variation in the unicellular, green alga Chlamydomonas reinhardtii.

ABSTRACT: Chlamydomonas reinhardtii is a model system for studying cilia, photosynthesis, and other core features of eukaryotes, and is also an emerging source of biofuels. Despite its importance to basic and applied biological research, the level and pattern of genetic variation in this haploid green alga has yet to be characterized on a genome-wide scale. To improve understanding of C. reinhardtii's genetic variability, we generated low coverage whole genome resequencing data for nearly all of the available isolates of this species, which were sampled from a number of sites in North America over the past ∼70 years. Based on the analysis of more than 62,000 single nucleotide polymorphisms, we identified two groups of isolates that represent geographical subpopulations of the species. We also found

SUBMITTER: Jang H 

PROVIDER: S-EPMC3405113 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature