A low level of serum total testosterone is independently associated with nonalcoholic fatty liver disease.

ABSTRACT:

Background

The association between low serum testosterone levels, visceral adipose tissue (VAT), and metabolic syndrome is now well known. However, the relationship between hepatic steatosis and serum testosterone levels has not been extensively studied. Our aim was to investigate the association of serum total testosterone levels with nonalcoholic fatty liver disease (NAFLD), adjusting for the influence of VAT and insulin resistance.

Methods

This study is a retrospective observational cross-sectional one of healthy Korean men and was conducted at the Seoul National University Hospital Healthcare System Gangnam Center. We used data obtained from 495 men who were at least 20 years of age and who had undergone blood testing, abdominal computed tomography, and ultrasonography.

SUBMITTER: Kim S 

PROVIDER: S-EPMC3406998 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature