Nitrogen dioxide levels estimated from land use regression models several years apart and association with mortality in a large cohort study.

ABSTRACT:

Background

Land Use Regression models (LUR) are useful to estimate the spatial variability of air pollution in urban areas. Few studies have evaluated the stability of spatial contrasts in outdoor nitrogen dioxide (NO₂) concentration over several years. We aimed to compare measured and estimated NO₂ levels 12 years apart, the stability of the exposure estimates for members of a large cohort study, and the association of the exposure estimates with natural mortality within the cohort.

Methods

We measured NO₂ at 67 locations in Rome in 1995/96 and 78 sites in 2007, over three one-week-long periods. To develop LUR models, several land-use and traffic variables were used. NO₂ concentration at each residential address was estimated for a cohort of 684,000 adults. We used Cox regr

SUBMITTER: Cesaroni G 

PROVIDER: S-EPMC3407745 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature