Unknown

Dataset Information

0

4-Methylenesterols from a sponge Theonella swinhoei.

ABSTRACT: Three new 4-methylenesterols, theonellasterol K (1), acetyltheonellasterol (2) and acetyldehydroconicasterol (3), along with two known sterols, theonellasterol (4) and theonellasterone (5), were isolated from the sponge Theonella swinhoei. The structures of these compounds were elucidated on the basis of their spectroscopic data and comparison of the NMR data with those of known analogues. Compound 1 exhibited significant cytotoxic activity against HCT-116, K562 and Molt 4 cancer cell lines.

SUBMITTER: Guo JK 

PROVIDER: S-EPMC3407929 | biostudies-literature |

REPOSITORIES: biostudies-literature

Json Xml

Similar Datasets

Unknown A serendipitous discovery of isomotuporin-containing sponge populations of Theonella swinhoei.
| S-EPMC4028065 | biostudies-literature
Unknown Paltolides A--C, anabaenopeptin-type peptides from the palau sponge Theonella swinhoei.
| S-EPMC2885440 | biostudies-literature
Unknown New tridecapeptides of the theonellapeptolide family from the Indonesian sponge Theonella swinhoei.
| S-EPMC3778368 | biostudies-literature
Unknown Theopapuamide, a cyclic depsipeptide from a Papua New Guinea lithistid sponge Theonella swinhoei.
| S-EPMC2566935 | biostudies-literature
Unknown Culturable associated-bacteria of the sponge Theonella swinhoei show tolerance to high arsenic concentrations.
| S-EPMC4340220 | biostudies-literature
Unknown Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei.
| S-EPMC528957 | biostudies-literature
Genomics Theonella swinhoei
| PRJNA260650 | ENA
Unknown Theonellamide G, a potent antifungal and cytotoxic bicyclic glycopeptide from the Red Sea marine sponge Theonella swinhoei.
| S-EPMC4012434 | biostudies-literature
Unknown Inhabitancy of active Nitrosopumilus-like ammonia-oxidizing archaea and Nitrospira nitrite-oxidizing bacteria in the sponge Theonella swinhoei.
| S-EPMC4844951 | biostudies-literature
Unknown Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei.
| S-EPMC3509528 | biostudies-literature