Pathology of drug-eluting versus bare-metal stents in saphenous vein bypass graft lesions.

ABSTRACT:

Objectives

The purpose of this study was to assess the pathological responses of atherosclerotic saphenous vein bypass grafts (SVBGs) to drug-eluting stents (DES) versus bare-metal stents (BMS).

Background

Repeat bypass surgery is typically associated with a high rate of morbidity and mortality. Percutaneous coronary interventions have emerged as the preferred treatment; however, only limited data are available on SVBGs pathological responses to DES and BMS.

Methods

Formalin-fixed SVBG of >2 years duration (n = 31) were collected to histologically characterize advanced atherosclerotic lesions in native SVBG. In a separate group, SVBGs treated with DES (n = 9) and BMS (n = 9) for >30 days duration were assessed for morphological and morphometric changes.

Results

SUBMITTER: Yazdani SK 

PROVIDER: S-EPMC3407956 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature