Comparative analysis of the genomes of two field isolates of the rice blast fungus Magnaporthe oryzae.

ABSTRACT: Rice blast caused by Magnaporthe oryzae is one of the most destructive diseases of rice worldwide. The fungal pathogen is notorious for its ability to overcome host resistance. To better understand its genetic variation in nature, we sequenced the genomes of two field isolates, Y34 and P131. In comparison with the previously sequenced laboratory strain 70-15, both field isolates had a similar genome size but slightly more genes. Sequences from the field isolates were used to improve genome assembly and gene prediction of 70-15. Although the overall genome structure is similar, a number of gene families that are likely involved in plant-fungal interactions are expanded in the field isolates. Genome-wide analysis on asynonymous to synonymous nucleotide substitution rates revealed that many i

SUBMITTER: Xue M 

PROVIDER: S-EPMC3410873 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature