Yeast 5 - an expanded reconstruction of the Saccharomyces cerevisiae metabolic network.

ABSTRACT:

Background

Efforts to improve the computational reconstruction of the Saccharomyces cerevisiae biochemical reaction network and to refine the stoichiometrically constrained metabolic models that can be derived from such a reconstruction have continued since the first stoichiometrically constrained yeast genome scale metabolic model was published in 2003. Continuing this ongoing process, we have constructed an update to the Yeast Consensus Reconstruction, Yeast 5. The Yeast Consensus Reconstruction is a product of efforts to forge a community-based reconstruction emphasizing standards compliance and biochemical accuracy via evidence-based selection of reactions. It draws upon models published by a variety of independent research groups as well as information obtained from biochemica

SUBMITTER: Heavner BD 

PROVIDER: S-EPMC3413506 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature