Genome-wide analysis of acetivibrio cellulolyticus provides a blueprint of an elaborate cellulosome system.

ABSTRACT:

Background

Microbial degradation of plant cell walls and its conversion to sugars and other byproducts is a key step in the carbon cycle on Earth. In order to process heterogeneous plant-derived biomass, specialized anaerobic bacteria use an elaborate multi-enzyme cellulosome complex to synergistically deconstruct cellulosic substrates. The cellulosome was first discovered in the cellulolytic thermophile, Clostridium thermocellum, and much of our knowledge of this intriguing type of protein composite is based on the cellulosome of this environmentally and biotechnologically important bacterium. The recently sequenced genome of the cellulolytic mesophile, Acetivibrio cellulolyticus, allows detailed comparison of the cellulosomes of these two select cellulosome-producing bacteria.

SUBMITTER: Dassa B 

PROVIDER: S-EPMC3413522 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature