Unsedated peroral wireless pH capsule placement vs. standard pH testing: a randomized study and cost analysis.

ABSTRACT:

Background

Wireless capsule pH-metry (WC) is better tolerated than standard nasal pH catheter (SC), but endoscopic placement is expensive.

Aims

to confirm that non-endoscopic peroral manometric placement of WC is as effective and better tolerated than SC and to perform a cost analysis of the available esophageal pH-metry methods.

Methods

Randomized trial at 2 centers. Patients referred for esophageal pH testing were randomly assigned to WC with unsedated peroral placement or SC after esophageal manometry (ESM). Primary outcome was overall discomfort with pH-metry. Costs of 3 different pH-metry strategies were analyzed: 1) ESM + SC, 2) ESM + WC and 3) endoscopically placed WC (EGD + WC) using publicly funded health care system perspective.

Results

86 patients (m

SUBMITTER: Andrews CN 

PROVIDER: S-EPMC3413593 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature