Risks for impaired cerebral autoregulation during cardiopulmonary bypass and postoperative stroke.

ABSTRACT:

Background

Impaired cerebral autoregulation may predispose patients to cerebral hypoperfusion during cardiopulmonary bypass (CPB). The purpose of this study was to identify risk factors for impaired autoregulation during coronary artery bypass graft, valve surgery with CPB, or both and to evaluate whether near-infrared spectroscopy (NIRS) autoregulation monitoring could be used to identify this condition.

Methods

Two hundred and thirty-four patients were monitored with transcranial Doppler and NIRS. A continuous, moving Pearson's correlation coefficient was calculated between mean arterial pressure (MAP) and cerebral blood flow (CBF) velocity, and between MAP and NIRS data, to generate the mean velocity index (Mx) and cerebral oximetry index (COx), respectively. Functional a

SUBMITTER: Ono M 

PROVIDER: S-EPMC3415287 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature