A pursuit of lineage-specific and niche-specific proteome features in the world of archaea.

ABSTRACT:

Background

Archaea evoke interest among researchers for two enigmatic characteristics -a combination of bacterial and eukaryotic components in their molecular architectures and an enormous diversity in their life-style and metabolic capabilities. Despite considerable research efforts, lineage- specific/niche-specific molecular features of the whole archaeal world are yet to be fully unveiled. The study offers the first large-scale in silico proteome analysis of all archaeal species of known genome sequences with a special emphasis on methanogenic and sulphur-metabolising archaea.

Results

Overall amino acid usage in archaea is dominated by GC-bias. But the environmental factors like oxygen requirement or thermal adaptation seem to play important roles in selection of residues

SUBMITTER: Roy Chowdhury A 

PROVIDER: S-EPMC3416665 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature