A longitudinal cohort based association study between uric acid level and metabolic syndrome in Chinese Han urban male population.

ABSTRACT:

Background

It has been recently demonstrated that serum uric acid (UA) is associated with metabolic syndrome (MetS) or its related clinical indications based on cross-sectional or prospective cohort studies. Nonetheless, due to the fact that UA level constantly fluctuates from time to time even for the person, using a single measure of UA level at baseline of those studies may not be sufficient for estimating the UA-Mets association.

Methods

To further estimate this time-dependent association, we fitted a generalized estimating equation (GEE) regression model with data from a large-scale 6-year longitudinal study, which included 2222 participants aged > =25 years with an average of 3.5 repeated measures of UA per person in the Health Management Center of Shandong Provincial

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC3416673 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature