Glutathione S-transferase M1 gene polymorphism and laryngeal cancer risk: a meta-analysis.

ABSTRACT:

Background and objectives

Studies investigating the association between glutathione S-transferase M1 (GSTM1) gene polymorphism and laryngeal cancer risk have reported conflicting results. The aim of the present study was to conduct a meta-analysis assessing the possible associations of GSTM1 gene polymorphism with laryngeal cancer risk.

Methods

The relevant studies were identified through a search of PubMed, Embase, ISI Web of Knowledge and Chinese National Knowledge Infrastructure until May 2011 and selected on the basis of the established inclusion criteria for publications, then a meta-analysis was performed to quantitatively summarize association of GSTM1 polymorphism with laryngeal cancer susceptibility.

Results

Seventeen studies were included in the present meta

SUBMITTER: Ying XJ 

PROVIDER: S-EPMC3416752 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature