Dietary fat quality and risk of sudden cardiac death in women.

ABSTRACT:

Background

Dietary n-3 PUFAs are inversely associated with risk of sudden cardiac death (SCD); however, little is known about other fats and SCD. Furthermore, concerns have been raised that high n-6 PUFA intake may attenuate the benefits of n-3 PUFAs.

Objective

We examined associations and selected interactions between dietary fatty acids, expressed as a proportion of total fat and SCD.

Design

We conducted a prospective cohort study among 91,981 women aged 34-59 y from the Nurses' Health Study in 1980. Over 30 y, we documented 385 SCDs.

Results

In multivariable models, women in the highest compared with the lowest quintile of SFA intake had an RR of SCD of 1.44 (95% CI: 1.04, 1.98). Conversely, women in the highest compared with the lowest quintile of PUFA inta

SUBMITTER: Chiuve SE 

PROVIDER: S-EPMC3417213 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature