β-Carotene in Golden Rice is as good as β-carotene in oil at providing vitamin A to children.

ABSTRACT:

Background

Golden Rice (GR) has been genetically engineered to be rich in β-carotene for use as a source of vitamin A.

Objective

The objective was to compare the vitamin A value of β-carotene in GR and in spinach with that of pure β-carotene in oil when consumed by children.

Design

Children (n = 68; age 6-8 y) were randomly assigned to consume GR or spinach (both grown in a nutrient solution containing 23 atom% ²H₂O) or [²H₈]β-carotene in an oil capsule. The GR and spinach β-carotene were enriched with deuterium (²H) with the highest abundance molecular mass (M) at M(β-C)+²H₁₀. [¹³C₁₀]Retinyl acetate in an oil capsule was administered as a reference dose. Serum samples collected from subjects were analyzed by using gas chromatography electron-capture negative chemical

SUBMITTER: Tang G 

PROVIDER: S-EPMC3417220 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature