Copper-catalyzed oxytrifluoromethylation of unactivated alkenes.

ABSTRACT: A mild, versatile, and convenient method for the efficient oxytrifluoromethylation of unactivated alkenes based on a copper-catalyzed oxidative difunctionalization strategy has been developed. This methodology provides access to a variety of classes of synthetically useful CF(3)-containing building blocks from simple starting materials.

SUBMITTER: Zhu R 

PROVIDER: S-EPMC3419474 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature