Identification and profiling of circulating antigens by screening with the sera from schistosomiasis japonica patients.

ABSTRACT:

Background

Schistosomiasis is a chronic disease caused by trematode flatworms of the genus Schistosoma. The disease remains a serious public health problem in endemic countries and affects at least 207 million people worldwide. A definite diagnosis of the disease plays a key role in the control of schistosomiasis. The detection of schistosome circulating antigens (CAs) is an effective approach to discriminate between previous exposure and current infection. Different methods have been investigated for detecting the CAs. However, the components of the schistosome CAs remain unclear. In this study, we analyzed the CAs in sera of patients infected with Schistosoma japonicum.

Methods

The parasites were collected from the infected rabbits for preparing the adult worm antigen (AWA

SUBMITTER: Lu Y 

PROVIDER: S-EPMC3419666 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature