Compositional stability of a salivary bacterial population against supragingival microbiota shift following periodontal therapy.

ABSTRACT: Supragingival plaque is permanently in contact with saliva. However, the extent to which the microbiota contributes to the salivary bacterial population remains unclear. We compared the compositional shift in the salivary bacterial population with that in supragingival plaque following periodontal therapy. Samples were collected from 19 patients with periodontitis before and after periodontal therapy (mean sample collection interval, 25.8 ± 2.6 months), and their bacterial composition was investigated using barcoded pyrosequencing analysis of the 16S rRNA gene. Phylogenetic community analysis using the UniFrac distance metric revealed that the overall bacterial community composition of saliva is distinct from that of supragingival plaque, both pre- and post-therapy. Temporal variation foll

SUBMITTER: Yamanaka W 

PROVIDER: S-EPMC3420916 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature