Comparison of dose decrement from intrafraction motion for prone and supine prostate radiotherapy.

ABSTRACT:

Background and purpose

Dose effects of intrafraction motion during prone prostate radiotherapy are unknown. We compared prone and supine treatment using real-time tracking data to model dose coverage.

Material and methods

Electromagnetic tracking data were analyzed for 10 patients treated prone, and 15 treated supine, with IMRT for localized prostate cancer. Plans were generated using 0 mm, 3 mm, and 5mm PTV expansions. Manual beam-hold interventions were applied to reposition the patient when translations exceeded a predetermined threshold. A custom software application (SWIFTER) used intrafraction tracking data acquired during beam-on model delivered prostate dose, by applying rigid body transformations to the prostate structure contoured at simulation within the planned d

SUBMITTER: Olsen JR 

PROVIDER: S-EPMC3423556 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature