XatA, an AT-1 autotransporter important for the virulence of Xylella fastidiosa Temecula1.

ABSTRACT: Xylella fastidiosa Temecula1 is the causative agent of Pierce's disease of grapevine, which is spread by xylem-feeding insects. An important feature of the infection cycle is the ability of X. fastidiosa to colonize and interact with two distinct environments, the xylem of susceptible plants and the insect foregut. Here, we describe our characterization of XatA, the X. fastidiosa autotransporter protein encoded by PD0528. XatA, which is classified as an AT-1 (classical) autotransporter, has a C-terminal β-barrel domain and a passenger domain composed of six tandem repeats of approximately 50 amino acids. Localization studies indicate that XatA is present in both the outer membrane and membrane vesicles and its passenger domain can be found in the supernatant. Moreover, XatA is important fo

SUBMITTER: Matsumoto A 

PROVIDER: S-EPMC3426408 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature