Molecular characterization of surface antigen 3 (SAG3) gene of Toxoplasma gondii RH-IVRI strain.

ABSTRACT: Toxoplasmosis, caused by Toxoplasma gondii, is a zoonotic disease and is responsible for abortions, stillbirth, and neonatal complications in livestock, especially in sheep, goats, and pigs. The molecular characterization of the parasite having global distribution is considered important to delineate the phylogenetic relationship among different isolates/strains of the parasite. The present communication deals with the molecular cloning and sequence analysis of the 1,158 bp entire open reading frame of surface antigen 3 (SAG3) of T. gondii RH strain being maintained at the Indian Veterinary Research Institute (IVRI). The sequence comparison analysis revealed 99.9 % homology with the published sequence of T. gondii RH strain, with a single substitution of guanine 'G' instead of adenine 'A'

SUBMITTER: Vikrant Sudan 

PROVIDER: S-EPMC3427684 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature